Why screen your at-risk patients for HBV?
Identify your patients with chronic hep B
In the US, the approximately 2.2 million people living with chronic hep B go largely undiagnosed and untreated.4,5
About 2 out of 3 people with CHB in the US are unaware of their infection2
Do you have patients with undiagnosed CHB?
Screen patients to reduce the transmission of HBV infection
CHB patients who are unaware of their infection are at risk for transmitting the virus to others.6 Screen at-risk patients to:
Identify chronically infected patients and allow for intervention to prevent transmission
Identify unprotected patients and link them to HBV vaccination9
Chronic hep B can cause serious complications
Patients who don’t experience symptoms may not recognize appropriate disease management in avoiding serious consequences.
CHB disease progression
bChronic infection is defined as HBsAg+ for ≥6 months.12HBsAg=hepatitis B surface antigen.
Risk factors associated with cirrhosis and HCC13,14
|>40 years of age|
|Family history of HCC|
|Born in Sub-Saharan Africa or Asia|
|Viral / Disease Factors||Cirrhosis13||HCC13,14|
|High viral load (>2000 IU/mL)|
|High serum AFP|
|Prolonged time to HBeAg seroconversion|
|Development of HBeAg-negative CHB|
|BCP or PC mutations|
|Presence of cirrhosis|
|HCV, HIV, or HDV coinfections|
|Heavy alcohol use|
|Metabolic syndrome (obesity, diabetes)|
“Implementing steps to identify, follow, refer, and [appropriately] treat persons with CHB infection by all primary care and specialist healthcare providers can have a major impact on reducing the occurrence of HCC and cirrhosis in infected persons.”